Methods
We are committed to being question-driven and not technique-limited, meaning that we seek to use the best existing methods and often build new tools and invent new procedures to pursue our research goals.
BioLuminescence & OptoGenetics
(BL-OG)
BL-OG combines chemo- and optogenetics to control and image cells.
Electrophysiology
We record with tetrodes, laminar probes, glass pipettes, and more.
Sensory Behavior
Mouse whisker mechanoreception is processed in the barrel cortex; this system is a model for in vivo sensory processing.
Computational Modeling
We construct biophysically precise computational models of neocortex, especially in collaboration with Drs. Stephanie R. Jones and Michael Frank.
Imaging
2-Photon, Intrinsic and Low Photon Count, Bioluminescence, Wide Field Imaging
Optogenetics
In addition to developing bioluminescence-driven optogenetics, our lab uses a variety of traditional optogenetic actuators and indicators. Currently, we employ calcium and dopamine indicators, and we are developing novel applications of light-manipulation in vessels and choroid plexus tissue.
Mouse clipart #183024 from http://clipart-library.com.